January 18, 2024 - The PGxAI team, in collaboration with leading IT giants and academic institutions such as Pyxeda.ai, Microsoft, Stanford University, Meta, and Google, has announced promising initial results from testing an innovative machine learning classifier. This breakthrough in pharmacogenetics promises to radically change treatment approaches, making them more personalized and safer for each patient.
The developed ML classifier is the result of years of research and development in applying artificial intelligence to analyze patients' genetic markers and biomarkers. It allows for high-accuracy determination of the need for therapeutic regimen adjustments based on a person's unique genetic profile, reducing the risk of adverse reactions and increasing treatment efficacy.
Initial data show that the use of modern machine learning algorithms, including XGBoost, achieves high predictive accuracy. The system demonstrates significant sensitivity and specificity in identifying the need to adapt therapeutic regimens, opening new possibilities for clinical practice.
This achievement is just the first step towards creating a comprehensive decision-support system in the field of personalized medicine. Future plans include expanding the classifier's functionality by incorporating additional data and improving algorithms, which will allow for even more precise medical intervention tailored to the needs of each individual patient.
PGxAI and its partners express their gratitude to all project participants for their contribution to science and technology development and look forward to continuing successful collaboration in the future. This project exemplifies how collaborative efforts from specialists in different fields can lead to significant breakthroughs in medicine and improve the quality of life for patients worldwide.
An article with specific data will become available after the patent is secured in early spring. Until then, we can share that the current accuracy and F1 score are impressively high, demonstrating the model's balanced performance and its potential to revolutionize personalized treatment approaches.
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