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Overview

Advance Rheumatologic Care with Precision Pharmacogenomics

Personalize treatments for complex autoimmune and inflammatory conditions, minimize adverse effects, and elevate patient outcomes across your health system.
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Overview
Rheumatologic disorders—ranging from rheumatoid arthritis to lupus and gout—often involve intricate immunological pathways and varying patient responses. PGxAI’s Rheumatology module (PGxAtlas™) integrates comprehensive pharmacogenomics and real-world evidence to guide selection and dosing of disease-modifying antirheumatic drugs (DMARDs), biologics, and more. By aligning each patient’s genetic profile with targeted therapies, PGxAtlas™ reduces flare-ups, mitigates adverse reactions, and improves long-term joint and immune health.
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15+ critical drugs analyzed, including both traditional DMARDs and next-generation biologics.
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Actionable insights covering key genetic variants that influence drug metabolism and efficacy.
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AI-driven real-time recommendations that adapt to patients’ evolving clinical status.
Key Highlights
Serving every stakeholder in healthcare
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Disease-Modifying Drug Insights
Tailors therapies like methotrexate, sulfasalazine, and biologics for optimized response and minimal toxicity.
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Reduced Flares & Hospital Visits
Proactive dose adjustments and drug selection lower the risk of disease flares and complications.
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Real-World Data Integration
Continuous machine learning from patient outcomes ensures the most updated recommendations for your rheumatology team.
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EHR Compatibility
PGxAtlas™ integrates seamlessly with leading EHR systems, giving rheumatologists timely, in-workflow alerts.
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Reimbursable PGx Testing
Aligns with recognized CPT codes, making personalized rheumatologic care both feasible and cost-effective.
Clinical Impact
Serving every stakeholder in healthcare
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Fewer Treatment Failures
Strategic drug-gene matching reduces trial-and-error approaches, improving disease control and patient quality of life.
Lower Adverse Events
Genetic insights guide dosing to minimize liver toxicity, allergic reactions, and other side effects often associated with DMARDs or biologics.
Improved Care Coordination
Rheumatologists, pharmacists, and primary care providers can easily collaborate via shared PGx data, streamlining treatment decisions.
Enhanced Value-Based Metrics
By reducing hospital admissions, ER visits, and chronic flare-ups, health systems see improved patient satisfaction and potential reimbursement gains.
Drug Categories
PGxAI supports a wide range of rheumatologic therapies
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Traditional DMARDs:
Methotrexate, Leflunomide, Sulfasalazine
Biologics:
TNF inhibitors (Etanercept, Infliximab), IL-6 inhibitors (Tocilizumab)
Anti-Gout Treatments:
Allopurinol, Febuxostat, Pegloticase
JAK Inhibitors:
Tofacitinib, Baricitinib
Immunomodulators:
Azathioprine, Hydroxychloroquine. Each recommendation is backed by validated genetic data (e.g., CYP2C9, TPMT) and robust clinical research.
Integration
Seamless EHR Integration
PGxAtlas™ is built for enterprise-level adoption, ensuring:
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Security
HIPAA & SOC 2 compliance ensures patient privacy and data integrity.
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Automations
Automated alerts for high-risk gene-drug interactions.
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Analytics
Customizable dashboards for oncology pharmacists, oncologists, and care coordinators.
Case Study
Summit Infectious Disease Center
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Challenge
Frequent DMARD failures leading to high rates of flare-ups and steroid dependency.
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Solution
PGxAtlas™ integrated into the EHR, guiding methotrexate dosing and biologic selection based on patient genetics.
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Results
25% reduction in disease flare severity over 9 months, improved medication adherence, and decreased reliance on high-dose steroids.
“PGxAI has empowered us to prescribe with far more precision, reducing the time and expense of treatment adjustments and truly improving our patients’ quality of life.”
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Dr. Alexandra Brennan
Lead Rheumatologist, Highland Rheumatology
Whats next
Ready to Shape the Future of Precision Medicine?
Empower your rheumatology teams with AI-driven pharmacogenomics that reduce flares, lower adverse events, and elevate patient satisfaction across every stage of care.
Contact Our Rheumatology Team
Discuss pilot programs and EHR integration strategies
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Request a Demo
Experience PGxAtlas™ in action for your rheumatology workflows.
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Learn More About EHR Integration
Discover secure, scalable solutions for multi-site deployments.
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